Montelukast Sodium is a selective cysteinyl leukotriene receptor antagonist that shows anti-inflammatory and bronchodilating activities. It actively blocks the cysteinyl leukotriene 1 receptor, which binds the inflammatory mediator leukotriene D4. Due to the inhibition of LTD4 activity leads to inhibition of leukotriene-mediated inflammatory events. The CysLT1 receptor is found spleen, lung, placenta, small intestine, and nasal mucosa, include monocyte/macrophages, mast cells, eosinophils, CD34-positive hemopoietic progenitor cells, neutrophils and endothelial cells.
Class of Drugs – A selective cysteinyl leukotriene receptor antagonist
Molecular Formula – C35H35ClNNaO3S
Molecular Weight - 608.2 g/mol
Working: Given medication acts as leukotriene receptor antagonists decrease inflammation and nasal congestion. It also helps to prevent reactions to triggers by retaining the airways to the lungs open. Montelukast Sodium improves symptoms of asthma as well as seasonal and year-round allergies. It prevents breathing problems during or after exercise.
Uses: This particular medication prevents the wheezing and shortness of breath caused by asthma and reduces the number of asthma attacks. Montelukast Sodium is used before exercise to prevent breathing problems during exercise. It reduces the number of times anyone needs to use the rescue inhaler. This drug is also used to relieve symptoms of hay fever and allergic rhinitis like sneezing, stuffy/runny/itchy nose. It should not be used right away and treat sudden asthma attacks or other breathing problems.
It blocks a certain natural substance that may cause or worsen asthma and allergies that make breathing easier by reducing swelling in the airways.
Popular Brands and Dosages: This medication used in popular brand medicine as given below:
- Singulair Chewable: 4 mg and 5 mg CT
Do not consume more than one dose in 24 hours.