Duloxetine is used as the main active ingredient in the medications that treat Major Depressive Disorder. It is the hydrochloride salt of duloxetine, which is a fluoxetine derivative that belongs to the class of selective serotonin and norepinephrine reuptake inhibitors. It exhibits antidepressant activity. This active component prevents the reuptake via transporter complexes on the pre-synaptic membrane. So as to increase the level of neurotransmitters within the synaptic cleft. This leads to potentiates serotonergic and noradrenergic activities in the central nervous system. It alleviates depression and neuropathy sensations, like pain and tingling.
Class of Drugs – A selective serotonin and norepinephrine reuptake inhibitors
Molecular Formula – C18H19NOS
Molecular Weight - 297.4 g/mol
Working: This active component Duloxetine prevents the reuptake of serotonin and epinephrine by nerves after they have been released. Uptake is an important mechanism for the removal of released neurotransmitters and terminates their actions on adjacent nerves. The reduced uptake caused by this medication increases the effect of serotonin and norepinephrine in the brain.
Uses: This given medication treats a major depressive disorder, diabetic peripheral neuropathic pain, generalized anxiety disorder, fibromyalgia, and chronic musculoskeletal pain effectively.
Popular Brands and Dosages: The given medicine Duloxetine is used to treat conditions like major depressive disorder. Popular brands of this component are as follows:
- Irenka: 20 mg, 30 mg, 40 mg, and 60 mg
- Drizalma Sprinkle: 20 mg, 30 mg, 40 mg, and 60 mg
- Cymbalta: 20 mg, 30 mg, 40 mg, and 60 mg
Consult the doctor before taking this pill.