Nimodipine is an analog of the calcium channel blocker that shows antihypertensive activity. His ingredient works by inhibiting the transmembrane influx of calcium ions to depolarization in smooth muscle cells so as to inhibit the vascular smooth muscle contraction. It induces vasodilatation. It affects cerebral arteries than on peripheral smooth muscle cells and myocardial cells. Later this factor inhibits the drug efflux pump P-glycoprotein that overexpressed in some multi-drug resistant tumors and improves the efficacy of some antineoplastic agents.
Class of Drugs – Calcium channel blocker
Molecular Formula – C21H26N2O7
Molecular Weight - 418.4 g/mol
Working: This medication acts by relaxing blood vessels which are narrow bases present in the brain near the area of bleeding so blood can flow more easily. Nimodipine also reduces brain damage. This active ingredient is used in medication that may also be used to reduce the problems due to stroke.
Uses: It is used to reduce problems due to a certain type of bleeding in the brain such as subarachnoid hemorrhage-SAH. This active component called a calcium channel blocker. The body naturally responds to bleeding by shrinking the blood vessel to slow blood flow. The bleeding is in the brain, restricting blood flow causes more brain damage. Nimodipine works by relaxing narrowed blood vessels in the brain so blood can flow more easily. This process and effects decrease brain damage.
Popular Brands and Dosages: This active component is used in popular brand medication as mentioned below:
- Nimotop: 30 mg
This ingredient is usually started as soon as possible after the start of bleeding in the brain generally within 4 days.