Losartan Potassium is a non-peptide angiotensin II receptor antagonist that shows antihypertensive activity. This component binds to the angiotensin II receptor and blocks the binding of angiotensin II to the receptor. Thus, it promotes vasodilatation and counteracting the effects of aldosterone. Angiotensin II stimulates the adrenal cortex to secrete aldosterone that decreases the sodium excretion and increases potassium excretion, which acts as a vasoconstrictor in vascular smooth muscle.
Class of Drugs – Angiotensin receptor blockers
Molecular Formula – C22H22ClKN6O
Molecular Weight - 461 g/mol
Working: This mentioned medicine helps treat high blood pressure. Due to high blood pressure and left ventricular hypertrophy the risk of stroke increases, so lower blood pressure reduces the risk. Reduced blood pressure also reduces the risk of kidney damage. This is due to high blood pressure raises the risk of kidney damage that’s caused by the high blood sugar levels linked with diabetes.
Uses: Angiotensin receptor blocker active component Losartan Potassium is approved for the treatment of high blood pressure i.e. hypertension. It helps to protect the kidneys from damage due to diabetes. It is also indicated to lower the risk of strokes in people with high blood pressure and an enlarged heart. Reducing high blood pressure prevents strokes, heart attacks, and kidney problems. This medication relaxes the blood vessels so that blood can flow more easily.
Popular Brands and Dosages: Given Losartan Potassium medicine is used as the main active component in a popular brand medicine as mentioned below:
- Cozaar: 25 mg, 50 mg, and 100 mg
Aged people may be more sensitive to the side effects of this medication, especially drowsiness, dizziness, and lightheadedness. It can increase the risk of falling. It should be used with caution.