Valsartan is an active medicine, which is a nonpeptide triazole-derived antagonist of angiotensin II with antihypertensive properties. This drug selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor in vascular smooth muscle and the adrenal gland. It prevents AT II-mediated vasoconstriction, aldosterone synthesis and secretion, and renal reabsorption of sodium. This leads to vasodilation, increased excretion of sodium and water, a reduction in plasma volume, and a reduction in blood pressure.
Class of Drugs – Angiotensin II receptor blockers
Molecular Formula – C24H29N5O3
Molecular Weight - 435.5 g/mol
Working: This mentioned active component belongs to a group of drugs called angiotensin II receptor blockers. Valsartan acts by blocking the effect of angiotensin. It makes blood vessels to relax more. It allows the kidney to get rid of extra water and salt. It helps lower blood pressure.
Uses: Given medication is indicated to treat high blood pressure and heart failure. This active component is also approved to improve the chance of living longer after a heart attack. In people with heart failure, Valsartan may also lower the chance of having to go to the hospital for heart failure. This drug is an angiotensin receptor blocker that works by relaxing blood vessels so that blood can flow more easily. Decreasing high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Popular Brands and Dosages: This active component is used in a popular brand medicine as given below:
- Diovan: 40 mg, 80 mg, and 160 mg