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What is Depakote?

Depakote (divalproex sodium) affects chemicals in the body that may be involved in causing seizures.

What is Depakote used for?

Depakote is used to treat various types of seizure disorders. This medicine is sometimes used together with some other seizure medications.
Depakote is also used for treating manic episodes related to bipolar disorder (manic depression), and to prevent migraine headaches.

When did the U.S. Food and Drug Administration (FDA) approve the medication?

Depakote was first approved by the FDA in 1996.

Can children take Depakote?

Children under the age of two are at higher risk for liver damage when consuming this medication. Talk to the child’s doctor about the risks of using this medication.

Are there potential interaction for people taking Depakote and any other drugs?

Some of the drugs intracting with Depakote include hepatic enzyme-inducing drugs, aspirin, carbapenem antibiotics, diazepam, ethosuximide, lamotrigine, phenytoin, amitriptyline, nortriptyline, warfarin, zidovudine, and topiramate.

What is the typical dose that would be prescribed with Depakote?

The FDA recommends that dosage for treating mania begin at 750 mg daily. The maximum recommended dosage is 60mg/kg per day.