Pilocarpine Hydrochloride is a natural alkaloid obtained from plants of the genus Pilocarpus that shows cholinergic agonist activity. This ingredient binds to muscarinic receptors so as to induce the exocrine gland secretion and stimulate the smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. It also stimulates the sphincter pupillae to contract leads to miosis that stimulates the ciliary muscle to contract. It results in the spasm of accommodation that may cause a transitory rise in intraocular pressure. It may increase the outflow of aqueous humor.
Class of Drugs – Cholinergic agonists
Molecular Formula – C11H17ClN2O2
Molecular Weight - 244.72 g/mol
Working: This active component Pilocarpine Hydrochloride is indicated to reduce pressure inside the eye and treat dry mouth. It acts by activating cholinergic receptors of the muscarinic type that may induce the trabecular meshwork to open and the aqueous humor to drain from the eye.
Uses: This medication is approved for the treatment of symptoms of dry mouth due to certain immune diseases like Sjogren's syndrome or from saliva gland damage due to radiation therapies of the head/neck for cancer. This medication belongs to a class of drugs called cholinergic agonists. Pilocarpine Hydrochloride stimulates certain nerves to maximize the amount of saliva produces, making it easier and more comfortable to speak and swallow.
Popular Brands and Dosages: This cholinergic agonist active component is used in following popular brand medicine:
- Salagen: 5 mg
Drink plenty of fluids to avoid getting dehydrated. It helps this medicine to work properly.