Acitretin medicine is retinoid and vitamin A. It is used in the treatment of psoriasis. It can lead to an increase in serum aminotransferase levels. It actively plays the role of a keratolytic drug. This active component is considered to be an established second-line treatment for psoriasis and exerts its effect due to its antikeratinizing, antiinflammatory, and antiproliferative effect. It shows antineoplastic properties make it a useful agent for cancer prophylaxis.
Class of Drugs – Retinoid
Molecular Formula – C21H26O3
Molecular Weight - 326.4 g/mol
Working: Given drug, Acitretin is a type of drug called a retinoid. These drugs are closely related to
Vitamin A and work by slowing down cell growth in the skin. It acts at cytosolic proteins and intranuclear receptors. The metabolites of this component bind to retinoic acid receptors (RARs). In psoriasis and other disorders of keratinization, acitretin normalizes epidermal cell proliferation, differentiation, and cornification that stimulates differentiation and normalizes accelerated epidermopoiesis of the pathological epidermis
Uses: This medicine is used as the main active ingredient. This active component Acitretin is indicated for the treatment of severe psoriasis in adults. It should be prescribed only by those knowledgeable in the systemic use of retinoids. In females of reproductive potential, this drug should be reserved for non-pregnant women.
Popular Brands and Dosages: Given active component is used in popular medicines as mentioned below:
- Soriatane: 10 mg and 25 mg
- 8-MOP: 10 mg and 25 mg
- Rheumatrex: 10 mg and 25 mg
- Betnesol: 10 mg and 25 mg
Administer this pill as mentioned in the prescription by the doctor.