Mesalamine is an Aminosalicylate drug used as the main active ingredient in medicines. It is Aminosalicylic Acid and a monohydroxybenzoic acid that is salicylic acid substituted by an amino group. It plays the role of a non-steroidal anti-inflammatory drug. This component is an aromatic amine, an amino acid, a member of phenols, a monocarboxylic acid and a monohydroxybenzoic acid. It derives from salicylic acid.
Class of Drugs – Aminosalicylates
Molecular Formula – C7H7NO3
Molecular Weight - 153.14 g/mol
Working: The mechanism of action of this medication is not known. But it is believed by the scientists that it may work by reducing inflammation in the colon. In conditions like Ulcerative colitis and other inflammatory diseases, excessive production of chemicals occurred. The medication blocks the activity of cyclooxygenase and lipoxygenase so as to reduce the production of prostaglandins. Due to reduction prostaglandins, it decreases the inflammation in the colon and the symptoms of ulcerative colitis
Uses: It is indicated for the treatment of certain bowel diseases such as ulcerative colitis. It reduces symptoms of ulcerative colitis like diarrhea, rectal bleeding, and stomach pain. The pill Mesalamine belongs to a class of drugs known as aminosalicylates. It is helpful to decrease the swelling in the colon.
Popular Brands and Dosages: This effective active component is available in popular brands as mentioned below:
- Asacol: 400 mg and 800 mg
- Lialda: 400 mg and 800 mg
- Apriso: 400 mg and 800 mg
- Pentasa: 400 mg and 800 mg
Mesalamine should be taken as directed by the doctor, usually 4 times daily.